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HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant form

SKU: 7889204942

4.2
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HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant formHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

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Description

In the autosomal dominant form

A number of genes are fusion partners have been characterized| in particular the anaplastic lymphoma kinase gene on chromosome 2

KRT10 encodes a member of the type I (acidic) cytokeratin family

It may be involved in articular cartilage turnover and cartilage pathophysiology associated with osteoarthritis

the third member of the antizyme family

HtrA2 Polyclonal Antibody, 100ul[BT-AP04278] Polyclonal Antibodies In the autosomal dominant formHTRA2 encodes a serine protease. The HtrA serine peptidase 2 has been localized in the endoplasmic reticulum and interacts with an alternatively spliced form of mitogen activated protein kinase 14. The protein has also been localized to the mitochondria with release to the cytosol following apoptotic stimulus. The protein is thought to induce apoptosis by binding the apoptosis inhibitory protein baculoviral IAP repeat containing 4. Nuclear

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