KI2L2 Polyclonal Antibody, 50ul[BT-AP10678] Cellular Cultivation & Health Management Mutations in this gene have

Mutations in this gene have been associated with autosomal recessive megalencephaly

The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form

Contains 1 B30

Alternatively spliced transcript variants have been identified in this gene

|PTM:Phosphorylated when associated with the catalytic subunit

KI2L2 Polyclonal Antibody, 50ul[BT-AP10678] Cellular Cultivation & Health Management Mutations in this gene haveKiller cell immunoglobulin like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13. 4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4,