EF-1 Alpha1/2 Polyclonal Antibody, 100ul Immune Cell Analysis Studies of the rat homolog

Studies of the rat homolog indicate that the protein may primarily function to inhibit viral gene expression and induce an innate immunity to viral infection

Supports IL-2 independent and IL-4 independent growth of helper T-cells

GPNMB may be involved in growth delay and reduction of metastatic potential

Additional transcript variants have been described

Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined

EF-1 Alpha1/2 Polyclonal Antibody, 100ul Immune Cell Analysis Studies of the rat homologEEF1A1 encodes an isoform of the alpha subunit of the elongation factor 1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to