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Phospho-BRCA1 (S1524) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This member is a ligand

SKU: 79598428568

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Phospho-BRCA1 (S1524) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This member is a ligandBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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Description

This member is a ligand for VEGFR-1 (vascular endothelial growth factor receptor 1) and NRP-1 (neuropilin-1)

Facilitates T-cell receptor (TCR)-mediated GATA3 activation and optimal T-helper 2 (Th2) cytokine production by modulating NFKB1 and JUNB activities

A pseudogene of this gene is located on chromosome 22

Two alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

FGF17 encodes a member of the fibroblast growth factor (FGF) family

Phospho-BRCA1 (S1524) Polyclonal Antibody, 20ul Diagnostic Probes & Oligos This member is a ligandBRCA1 (BRCA1, DNA repair associated) encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi subunit protein complex known as the BRCA1 associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C terminal

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