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Sarcoglycan Alpha Polyclonal Antibody, 50ul Protein Modification This gene is a member

SKU: 79705133351

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Sarcoglycan Alpha Polyclonal Antibody, 50ul Protein Modification This gene is a memberSGCA (sarcoglycan alpha) encodes a component of the dystrophin glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in SGCA result in type 2D autosomal recessive limb girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for

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Description

This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding

PTM:Phosphorylated on serine residues by MAPK kinases upon insulin stimulation

The alpha-3 chain of type VI collagen is much larger than the alpha-1 and -2 chains

This intronless gene encodes a protein which contains several domains found in members of the DEAD-box helicase protein family

GO annotations related to this gene include actin binding and calmodulin binding

Sarcoglycan Alpha Polyclonal Antibody, 50ul Protein Modification This gene is a memberSGCA (sarcoglycan alpha) encodes a component of the dystrophin glycoprotein complex (DGC), which is critical to the stability of muscle fiber membranes and to the linking of the actin cytoskeleton to the extracellular matrix. Its expression is thought to be restricted to striated muscle. Mutations in SGCA result in type 2D autosomal recessive limb girdle muscular dystrophy. Multiple transcript variants encoding different isoforms have been found for

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