IRF3 Polyclonal Antibody, 20ul Capsule Filter An important paralog of this

An important paralog of this gene is PTGFRN

and interleukin 29 (IL29)

Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA-damaging agents

and it apparently protects neurons against oxidative stress and cell death

Indispensable in any laboratory setting

IRF3 Polyclonal Antibody, 20ul Capsule Filter An important paralog of thisIRF3 encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed