Bcl-2 Polyclonal Antibody, 50ul[BT-AP00857] Virus Packaging Initially assumed to be a

Initially assumed to be a pseudogene

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes

This protein contains conserved DLG (asp-leu-gly) and ENIL (glu-asn-ile-leu) motifs

These enzymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation

Bcl-2 Polyclonal Antibody, 50ul[BT-AP00857] Virus Packaging Initially assumed to be aBCL2 encodes an integral outer mitochondrial membrane protein (BCL2, apoptosis regulator) that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. Alternative splicing results in multiple transcript variants.