Trk B Polyclonal Antibody, 50ul[BT-AP09215] Antibody Development Syntaxin-1

Syntaxin-1

In the absence of mutations

This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36

This protein is a target for SMAD-specific E3 ubiquitin ligases| such as SMURF1 and SMURF2| and undergoes ubiquitination and proteasome-med

An important paralog of this gene is CDK14

Trk B Polyclonal Antibody, 50ul[BT-AP09215] Antibody Development Syntaxin-1NTRK2 encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternative splicing results in multiple transcript variants.