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OSBL8 Rabbit Polyclonal Antibody, 100ul Reagent Reservoirs This protein also contains an

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OSBL8 Rabbit Polyclonal Antibody, 100ul Reagent Reservoirs This protein also contains anThis gene encodes a member of a family of proteins containing an N terminal pleckstrin homology domain and a highly conserved C terminal oxysterol binding protein like sterol binding domain. It binds mutliple lipid containing molecules including phosphatidylserine phosphatidylinositol 4 phosphate (PI4P) and oxysterol and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple

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Description

This protein also contains an N-terminal phosphotyrosine binding domain that allows it to interact with numerous tyrosine-phosphorylated substrates and target them for proteasome degradation

Low expression of this gene may be related to higher survival rates in breast cancer patients

Knockout studies in mice suggest that this kinase is important for lipopolysaccharide (LPS)-mediated signaling in activated macrophages and may also play a role in controlling anxiety-like behavior

Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes

CRK encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins

OSBL8 Rabbit Polyclonal Antibody, 100ul Reagent Reservoirs This protein also contains anThis gene encodes a member of a family of proteins containing an N terminal pleckstrin homology domain and a highly conserved C terminal oxysterol binding protein like sterol binding domain. It binds mutliple lipid containing molecules including phosphatidylserine phosphatidylinositol 4 phosphate (PI4P) and oxysterol and promotes their exchange between the endoplasmic reticulum and the plasma membrane. Alternative splicing results in multiple

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