4E-BP1 Polyclonal Antibody, 100ul[BT-AP00038] Culture Tubes The encoded protein is conserved

The encoded protein is conserved among the mammalian Laurasiatheria branch

The protein encoded by PECAM1 (platelet and endothelial cell adhesion molecule 1) is found on the surface of platelets

It participates in an NF-kappaB-inducing signalling cascade common to receptors of the tumour-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor

Mutations in NOTCH1 are associated with aortic valve disease

and Fuchs endothelial corneal dystrophy

4E-BP1 Polyclonal Antibody, 100ul[BT-AP00038] Culture Tubes The encoded protein is conservedEIF4EBP1 encodes one member (eukaryotic translation initiation factor 4E binding protein 1) of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is