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PDH-E1 Alpha Monoclonal Antibody, 100ul Low retention tips Its protein inhibits activated C1r

SKU: 80138480307

4.6
USD135.00 USD185.00

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PDH-E1 Alpha Monoclonal Antibody, 100ul Low retention tips Its protein inhibits activated C1rThe pyruvate dehydrogenase (PDH) complex is a nuclear encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme

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Description

Its protein inhibits activated C1r and C1s of the first complement component and thus regulates complement activation

and other diseases

The acidic C-terminal region of the encoded protein can act as a transactivation domain

SERPINB9 encodes a member of the serine protease inhibitor family which are also known as serpins

The TRAF3-interacting JNK-activating modulator may also interact with a large multi-protein assembly containing the phosphatase 2A catalytic subunit

PDH-E1 Alpha Monoclonal Antibody, 100ul Low retention tips Its protein inhibits activated C1rThe pyruvate dehydrogenase (PDH) complex is a nuclear encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme

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