Mnk1 Polyclonal Antibody, 100ul[BT-AP05493] Yeast Expression The protein encoded by MATK

The protein encoded by MATK has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: sRC homology SH2 and SH3 domains

It functions as a repressor of TGF-beta signaling

The gene was shown to be amplified and overexpressed in 2 of 8 ovarian carcinoma cell lines and 2 of 15 primary ovarian tumors

The EPH receptor B1 encoded by EPHB1 is a receptor for ephrin-B family members

colon cancer with RER

Mnk1 Polyclonal Antibody, 100ul[BT-AP05493] Yeast Expression The protein encoded by MATKMKNK1 (MAP kinase interacting serine threonine kinase 1) encodes a Ser Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C terminal region of eIF4G. Alternatively spliced transcript variants have been noted for MKNK1.