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PDK2 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System Malonyl-CoA is an intermediate in

SKU: 80316684603

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PDK2 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System Malonyl-CoA is an intermediate inPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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Description

Malonyl-CoA is an intermediate in fatty acid biosynthesis| and also inhibits the transport of fatty acyl CoAs into mitochondria

This nuclear gene encodes polypeptide 1 (muscle isoform) of subunit VIIa and the polypeptide 1 is present only in muscle tissues

The encoded protein is localized to lipid rafts of the endoplasmic reticulum and plays a critical role in inositol 1|4|5-trisphosphate (IP3) signaling by mediating ER-associated degradation of activated IP3 receptors

It constitutes approximately 12% of the noncollagenous proteins in human bone and is synthesized by skeletal-associated cell types

Cholecystokinin B receptor is a type B gastrin receptor

PDK2 Polyclonal Antibody, 50ul Multi-Layer Cell Culture System Malonyl-CoA is an intermediate inPDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

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