Human Tumor Necrosis Factor Ligand Superfamily Member 11, TNFSF11 ELISA Kit, 96T Bottles Patients with mutations in this

Patients with mutations in this gene have altered levels of sphingolipid and phospholipids in the brain

The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions

PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation

which heterodimerizes with type I keratins to form hair and nails

tuberculosis HSP70 (dnaK) and HSP65 (groEL-2) act via this protein to stimulate NF-kappa-B expression (PubMed: 15809303)

Human Tumor Necrosis Factor Ligand Superfamily Member 11, TNFSF11 ELISA Kit, 96T Bottles Patients with mutations in this