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C5ARL Polyclonal Antibody, 50ul Peptide Modification Two main isozymes are known

SKU: 80398680077

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C5ARL Polyclonal Antibody, 50ul Peptide Modification Two main isozymes are knownThis gene encodes a G protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G protein coupled receptors, the encoded protein does not associate with intracellular G proteins. It may instead modulate signal transduction through the beta arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of

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Description

Two main isozymes are known to exist in eukaryotic cells: one is found in the mitochondrial matrix and the other in the cytoplasm

Alternatively spliced transcript variants varying in the 5' UTR have been found for this gene

and the testis

The protein encoded by this gene is phosphorylated by ZAP-70/Syk protein tyrosine kinases following activation of the T-cell antigen receptor (TCR) signal transduction pathway

Mutations in this gene are associated with methylmalonic aciduria and homocystinuria type cblC

C5ARL Polyclonal Antibody, 50ul Peptide Modification Two main isozymes are knownThis gene encodes a G protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G protein coupled receptors, the encoded protein does not associate with intracellular G proteins. It may instead modulate signal transduction through the beta arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of

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