AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing Guanine nucleotide exchange factors (GEFs)

Guanine nucleotide exchange factors (GEFs) accelerate the GTPase activity of Rho GTPases by catalyzing their release of bound GDP

CYP2D6 can vary in copy number and individuals with the ultrarapid metabolizer phenotype can have 3 or more active copies of the gene

leading to nonketotic hypoglycemia

This gene is clustered with genes and pseudogenes of the cell adhesion molecules subgroup of the CEA family on chromosome 19

Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis

AT2B3 Polyclonal Antibody, 20ul Shaker&Mixing Guanine nucleotide exchange factors (GEFs)The protein encoded by this gene belongs to the family of P type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate