DnaJC17 Polyclonal Antibody, 100ul Gene Editing Disks large homolog 2 forms

Disks large homolog 2 forms a heterodimer with a related family member that may interact at postsynaptic sites to form a multimeric scaffold for the clustering of receptors

or with the TCF3 (E2A) gene on chromosome 19

This gene and MAPK8 are also known as c-Jun N-terminal kinases

Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera

and are hypothesized to form part of the mitochondrial permeability transition pore

DnaJC17 Polyclonal Antibody, 100ul Gene Editing Disks large homolog 2 formsThe DnaJ family is one of the largest of all chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP