Internexin- Alpha Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene are

Mutations in this gene are responsible for as much as 50% of pre-lingual

TLEs are transcriptional co-repressors that bind to many transcription factors such as LEF1

It is found in mitochondria| peroxisomes| and the cytoplasm

Multiple transcript variants expressed from alternate promoters and encoding different isoforms have been found for this gene

thereby allowing them to fold correctly

Internexin- Alpha Polyclonal Antibody, 100ul Nucleic Acid Extraction Mutations in this gene areNeurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. INA (internexin neuronal intermediate filament protein alpha) is a member of the intermediate filament family and is involved in the morphogenesis of neurons.