HLA-DM beta Polyclonal Antibody, 20ul Buffer Solutions |Belongs to the dwarfin/SMAD family

|Belongs to the dwarfin/SMAD family

The encoded protein is expressed in endothelial cells

A mutation in this gene was found in a family with Stickler syndrome

This protein participates in a wide variety of cellular functions including lymphocyte activation

The C-terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho/TLE family members

HLA-DM beta Polyclonal Antibody, 20ul Buffer Solutions |Belongs to the dwarfin/SMAD familyHLA DMB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta (DMB) chain, both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP (class II associated invariant chain peptide) molecule from the peptide binding site. Class II molecules are expressed in