SPG7 Polyclonal Antibody, 100ul Tubes Voltage-dependent calcium channels are multisubunit

Voltage-dependent calcium channels are multisubunit complexes consisting of alpha-1

The encoded protein is thought to be involved in stereocilia organization and hair bundle formation

Redistributes to discrete nuclear foci upon DNA damage

The Ig-like V-type domain 2 mediates interaction with CXADR

The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates| including ADP-ribose (ADPR) and 8-oxoGua-containing 8-oxo-dADP and 8-oxo-dGDP

SPG7 Polyclonal Antibody, 100ul Tubes Voltage-dependent calcium channels are multisubunitThis gene encodes a mitochondrial metalloprotease protein that is a member of the AAA family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Mutations in this gene cause autosomal recessive spastic paraplegia 7. Two transcript variants encoding distinct isoforms have been identified.