Crk II(Phospho Tyr221) Polyclonal Antibody, 20ul Mini dry bath the SH2 domain targets SH2

the SH2 domain targets SH2 domain-containing proteins to tyrosine-phosphorylated sites

CRKL encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion

Based on known functions in these species

GO annotations related to this gene include protein homodimerization activity and intracellular calcium activated chloride channel activity

providing exceptional versatility for a range of laboratory applications

Crk II(Phospho Tyr221) Polyclonal Antibody, 20ul Mini dry bath the SH2 domain targets SH2This gene encodes a member of an adapter protein family that binds to several tyrosine phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2 phosphotyrosine interaction. The N terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C