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Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos which could bind and inhibit

SKU: 8133388313

4.0
SEK97.20 SEK140.20

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Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos which could bind and inhibitCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals

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Description

which could bind and inhibit the chaperone activity of Hsc70/Hsp70

the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes

It is regulated by a family of G protein-coupled receptors

CTU1 (cytosolic thiouridylase subunit 1)

Alternative splicing results in multiple transcript variants encoding distinct isoforms

Caspase12 Polyclonal Antibody, 20ul Diagnostic Probes & Oligos which could bind and inhibitCaspases are cysteine proteases that cleave C terminal aspartic acid residues on their substrate molecules. CASP12 is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of CASP12 mediates apoptosis in response to endoplasmic reticulum stress. However, in humans CASP12 contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals

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