AZ1 Polyclonal Antibody, 100ul Reservoirs Tumor suppressor

Tumor suppressor

The protein encoded by this gene functions as a transcriptional coactivator for nuclear hormone receptors

abolishes sinus arrhythmia

all encoding the same protein

Autoantibodies against this protein have been found in patients with cancer or graft versus host disease

AZ1 Polyclonal Antibody, 100ul Reservoirs Tumor suppressorThe protein encoded by OAZ1 belongs to the ornithine decarboxylase antizyme family, which plays a role in cell growth and proliferation by regulating intracellular polyamine levels. Expression of antizymes requires +1 ribosomal frameshifting, which is enhanced by high levels of polyamines. Antizymes in turn bind to and inhibit ornithine decarboxylase (ODC), the key enzyme in polyamine biosynthesis; thus, completing the auto regulatory circuit. OAZ1