STAG3 Polyclonal Antibody, 100ul ssDNA Synthesis Component of the probable SCF(FBXO7)

Component of the probable SCF(FBXO7) complex containing FBXO7

The gene product complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)

respectively

which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons

This binding is mediated by a unique sequence of 47 amino acids C-terminal to an SH3 domain

STAG3 Polyclonal Antibody, 100ul ssDNA Synthesis Component of the probable SCF(FBXO7)The stromal antigen 3 encoded by STAG3 is expressed in the nucleus and is a subunit of the cohesin complex which regulates the cohesion of sister chromatids during cell division. A mutation in this gene is associated with premature ovarian failure. Alternate splicing results in multiple transcript variants encoding distinct isoforms. This gene has multiple pseudogenes.