UBP4 Rabbit Polyclonal Antibody, 100ul Cryopreservation Freeman-Sheldon syndrome and Sheldon-Hall syndrome

Freeman-Sheldon syndrome and Sheldon-Hall syndrome

Following validation through diverse cell culture tests

The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles

Alternative splicing results in several additional transcript variants| some encoding different isoforms and others that have not been fully characterized

It is also a substrate for the cyclic AMP-dependent protein kinase

UBP4 Rabbit Polyclonal Antibody, 100ul Cryopreservation Freeman-Sheldon syndrome and Sheldon-Hall syndromeThe protein encoded by this gene is a protease that deubiquitinates target proteins such as ADORA2A and TRIM21. The encoded protein shuttles between the nucleus and cytoplasm and is involved in maintaining operational fidelity in the endoplasmic reticulum. Three transcript variants encoding different isoforms have been found for this gene.