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ER Alpha Polyclonal Antibody, 100ul[BT-AP03078] Molecular Sciences The protein encoded by this

SKU: 81672088422

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ER Alpha Polyclonal Antibody, 100ul[BT-AP03078] Molecular Sciences The protein encoded by thisESR1 encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein (estrogen receptor 1) localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone.

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Description

The protein encoded by this gene is a member of the DNA polymerase type-B-like family

a tumor suppressor protein related to APC/beta-catenin signaling pathway

5ul to 1ml

Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus

which suggested its role in tumorigenesis

ER Alpha Polyclonal Antibody, 100ul[BT-AP03078] Molecular Sciences The protein encoded by thisESR1 encodes an estrogen receptor, a ligand activated transcription factor composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein (estrogen receptor 1) localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but also play a role in other tissues such as bone.

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