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DNA Ligase I Polyclonal Antibody, 100ul NGS Oligos Members of this Type 1

SKU: 81762802457

4.3
SEK123.75 SEK151.75

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DNA Ligase I Polyclonal Antibody, 100ul NGS Oligos Members of this Type 1LIG1 encodes a member of the ATP dependent DNA ligase protein family. DNA ligase 1 functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA damaging agents. Disruption of LIG1 may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

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Description

Members of this Type 1 transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats

The protein encoded by this gene is a subunit of a bipartite UDP-N-acetylglucosamine transferase

printed at the sides of the plate and package bag facilitates quality traceability

This may also be true for mouse and human

Misregulation of this gene has been implicated in tumorigenesis

DNA Ligase I Polyclonal Antibody, 100ul NGS Oligos Members of this Type 1LIG1 encodes a member of the ATP dependent DNA ligase protein family. DNA ligase 1 functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA damaging agents. Disruption of LIG1 may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.

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