BACE2 Polyclonal Antibody, 20ul Metabolic enzymes Belongs to the interleukin-1 receptor

Belongs to the interleukin-1 receptor family

Chromosome 14 encodes the presinilin 1 (PSEN1) gene

The protein has a role in B-cell receptor signaling and B-cell development

This protein interacts with ACT (activator of CREM in testis) and may play a role in CREM (cAMP response element modulator)-ACT-mediated gene transcription during spermatogenesis

A related pseudogene has been identified on chromosome 19

BACE2 Polyclonal Antibody, 20ul Metabolic enzymes Belongs to the interleukin-1 receptorThis gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimer's disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.