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STXB2 Rabbit Polyclonal Antibody, 100ul Petri Dishes SOX6 (SRY-box 6) encodes a

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STXB2 Rabbit Polyclonal Antibody, 100ul Petri Dishes SOX6 (SRY-box 6) encodes aThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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Description

SOX6 (SRY-box 6) encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA

Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene

The encoded protein may be involved in sensory neuron regulation and in the modulation of pain

including the alpha subunit of the inhibin A and B protein complexes

The protein encoded by NDFIP1 (Nedd4 family interacting protein 1) belongs to a small group of evolutionarily conserved proteins with three transmembrane domains

STXB2 Rabbit Polyclonal Antibody, 100ul Petri Dishes SOX6 (SRY-box 6) encodes aThis gene encodes a member of the STXBP unc 18 SEC1 family. The encoded protein is involved in intracellular trafficking control of SNARE (soluble NSF attachment protein receptor) complex assembly and the release of cytotoxic granules by natural killer cells. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

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