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MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Conquer your research with LightNing™

SKU: 81942582990

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MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Conquer your research with LightNing™MDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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Description

Conquer your research with LightNing™ SmaI

Related pseudogenes are located on chromosomes 1 and 9

tissue specificity:Highly expressed in placental JEG-3 cells and very low levels of expression in non-steroidogenic cells

also known as F-actin bundling domain

ZC3H7B encodes a protein that contains a tetratricopeptide repeat domain

MDM2 Polyclonal Antibody, 100ul[BT-AP05300] Multiplex Immunoassays Conquer your research with LightNing™MDM2 encodes a nuclear localized E3 ubiquitin ligase. E3 ubiquitin protein ligase Mdm2 can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. MDM2 is itself transcriptionally regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript

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