HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation The encoded protein shares 100%

The encoded protein shares 100% sequence identity with the mouse and rat counterparts

Mutations in TRIP4 are associated with spinal muscular atrophy with congenital bone fractures-1 (SMABF1)

RAD52 homolog

Mutations in this gene are associated with autosomal dominant progressive external ophthalmoplegia-6 (PEOA6) and Seckel syndrome 8

This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB)

HERC3 Rabbit Polyclonal Antibody, 20ul Drug Development and Evaluation The encoded protein shares 100%This gene encodes a member the HERC ubiquitin ligase family. The encoded protein is located in the cytosol and binds ubiquitin via a HECT domain. Mutations in this gene have been associated with colorectal and gastric carcinomas. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.