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E2F-4/5 Polyclonal Antibody, 50ul Lysosome Transcripts from HIST4H4 lack polyA

SKU: 81972679609

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E2F-4/5 Polyclonal Antibody, 50ul Lysosome Transcripts from HIST4H4 lack polyAE2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which

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Description

Transcripts from HIST4H4 lack polyA tails

this gene is established as a protooncogene causally involved in the pathogenesis of lymphomas

resulting in expression of at least one isoform of myocyte-specific enhancer factor 2B (MEF2B) from this read-through locus

A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers

Defects in this gene are the cause of glycogen storage disease II| also known as Pompe's disease| which is an autosomal recessive disorder with a broad clinical spectrum

E2F-4/5 Polyclonal Antibody, 50ul Lysosome Transcripts from HIST4H4 lack polyAE2F transcription factor 4 encoded by E2F4 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which

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