SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 100ul Immunology IGF2BP2 encodes a member of

IGF2BP2 encodes a member of the IGF-II mRNA-binding protein (IMP) family

This gene encodes a member of the GIT protein family| which interact with G protein-coupled receptor kinases and possess ADP-ribosylation factor (ARF) GTPase-activating protein (GAP) activity

It is comprised of subunits linked by interchain disulfide bonds to form large| variably sized homomultimers

and is associated with spinocerebellar ataxia type 1 (SCA1)

hydrolyzing O-glycosyl compounds and chitinase activity

SLP-76(Phospho-Ser376) Rabbit Polyclonal Antibody, 100ul Immunology IGF2BP2 encodes a member ofSLP 76 was originally identified as a substrate of the ZAP 70 protein tyrosine kinase following T cell receptor (TCR) ligation in the leukemic T cell line Jurkat. The SLP 76 locus has been localized to human chromosome 5q33 and the gene structure has been partially characterized in mice. The human and murine cDNAs both encode 533 amino acid proteins that are 72% identical and comprised of three modular domains. The NH2 terminus contains an acidic