HNF-4 Alpha/Gamma Polyclonal Antibody, 50ul[BT-AP04161] Cell Culture Dishes active Rb proteins are hypophosphorylated

active Rb proteins are hypophosphorylated and bind to E2F transcription factors to repress transcription and inhibit cell cycle progression

The octamer wraps approximately 147 bp of DNA

Mutations in this gene are associated with interleukin 2 receptor alpha deficiency

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HNF-4 Alpha/Gamma Polyclonal Antibody, 50ul[BT-AP04161] Cell Culture Dishes active Rb proteins are hypophosphorylatedHepatocyte nuclear factor 4 alpha encoded by HNF4A is a nuclear transcription factor which binds DNA as a homodimer. The encoded protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This gene may play a role in development of the liver, kidney, and intestines. Mutations in this gene have been associated with monogenic autosomal