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BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction this protein forms a complex

SKU: 82454382150

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SEK123.75 SEK161.75

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BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction this protein forms a complexBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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Description

this protein forms a complex with STAT1 and IFN regulatory factor family protein p48 (ISGF3G)

including binding and protecting poly(U) termini of nascent RNA polymerase III transcripts from exonuclease digestion

Rudhira/BCAS3 (Breast Cancer Amplified Sequence 3) is a conserved protein expressed in the embryonic vasculature and malignant tumors

VGF is specifically expressed in a subpopulation of neuroendocrine cells

Knockout studies of the similar gene in mice implied the role of this protein in regulating proliferation and differentiation of midline cerebellar structures

BCL2L12 Polyclonal Antibody, 100ul Nucleic Acid Extraction this protein forms a complexBCL2L12 (BCL2 like 12) encodes a member of a family of proteins containing a Bcl 2 homology domain 2 (BH2). The encoded protein is an anti apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of BCL2L12 has been detected in a number of different cancers. There is a pseudogene for BCL2L12 on chromosome

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