Histone H2B Polyclonal Antibody, 50ul[BT-AP04029] Enzyme Activity Assays Deregulation of this gene may

Deregulation of this gene may play a role in several types of cancer including glioblastoma multiforme

The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status

This gene encodes a tumor suppressor protein that can induce cell growth arrest and apoptosis

2|q22) associated with T-cell acute lymphoblastic leukemia

including erythropoietin

Histone H2B Polyclonal Antibody, 50ul[BT-AP04029] Enzyme Activity Assays Deregulation of this gene mayH2BFS is a Pseudogene. Histone H2B type 1 H is a core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post translational modifications of histones, also called histone