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O-FucT-2 Polyclonal Antibody, 50ul ssDNA Synthesis a highly conserved enzyme with

SKU: 82701928631

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O-FucT-2 Polyclonal Antibody, 50ul ssDNA Synthesis a highly conserved enzyme withFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) like repeats or thrombospondin (THBS; see MIM 188060) type 1 repeats. POFUT2 is an O fucosyltransferase that use THBS type 1 repeats as substrates (Luo et al. 2006 [PubMed 16464857]).

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Description

a highly conserved enzyme with a strongly regulated expression

The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein

RNA Polymerase II

q14) leading to the fusion of this gene and the MLLT10 gene is found in acute lymphoblastic leukemia

The presence of potential DNA-binding and dimerization-transactivation domains suggests that this protein may act as a transcription factor

O-FucT-2 Polyclonal Antibody, 50ul ssDNA Synthesis a highly conserved enzyme withFucose is typically found as a terminal modification of branched chain glycoconjugates, but it also exists in direct O linkage to serine or threonine residues within cystine knot motifs in epidermal growth factor (EGF; MIM 131530) like repeats or thrombospondin (THBS; see MIM 188060) type 1 repeats. POFUT2 is an O fucosyltransferase that use THBS type 1 repeats as substrates (Luo et al. 2006 [PubMed 16464857]).

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