HECW1 Polyclonal Antibody, 100ul Pipette Micro Tips Built-in magnetic stirrer for a
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HECW1 Polyclonal Antibody, 100ul Pipette Micro Tips Built-in magnetic stirrer for aE3 ubiquitin protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.,pathway: Protein modification; protein ubiquitination.,Contains 1 C2 domain.,Contains 1 HECT (E6AP type E3 ubiquitin protein ligase) domain.,Contains 2 WW
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