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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conserved

SKU: 82920058729

4.6
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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conservedRFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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Description

with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters

It regulates fibrillogenesis by interacting with collagen fibrils and other extracellular matrix proteins

Defects in this gene are the cause of hypomagnesemia type 4

This gene encodes a protein that is one of the two components of elastic fibers

Functional analysis showed that this gene product has both ATPase and DNA helicase activities

RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator with the most highly conservedRFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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