Histone H2A.X Polyclonal Antibody, 100ul[BT-AP09933] Enzymes & Activity Assays May be required for tumorigenesis

May be required for tumorigenesis of a subset of gastric adenocarcinomas

Studies of the mouse ortholog have shown that the encoded protein catalyzes histone poly(ADP-ribosyl)ation and may be involved in T-cell function

SEPT1 encodes Septin-1 that can form homo- and heterooligomeric filaments

This nuclear enzyme is involved in processes such as chromosome condensation| chromatid separation| and the relief of torsional stress that occurs during DNA transcription and replication

NPHS1 encodes a member of the immunoglobulin family of cell adhesion molecules that functions in the glomerular filtration barrier in the kidney

Histone H2A.X Polyclonal Antibody, 100ul[BT-AP09933] Enzymes & Activity Assays May be required for tumorigenesisHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This