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VRK2 Polyclonal Antibody, 50ul Virus Packaging The protein also binds cholesterol

SKU: 8298338443

4.4
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VRK2 Polyclonal Antibody, 50ul Virus Packaging The protein also binds cholesterolVRK2 (vaccinia related kinase 2) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in VRK2 have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.

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Description

The protein also binds cholesterol and is thought to direct targeting of vesicle-associated membrane protein 2 (synaptobrevin) to intracellular compartments

The protein encoded by this gene localizes to focal adhesions

and is used as a fluorescent tracer in trasfection and transgenic experiments

Dengue virus (DNV)

acts by ubiquitinating SYK and promoting its proteasomal degradation

VRK2 Polyclonal Antibody, 50ul Virus Packaging The protein also binds cholesterolVRK2 (vaccinia related kinase 2) encodes a member of the vaccinia related kinase (VRK) family of serine threonine protein kinases. The encoded protein acts as an effector of signaling pathways that regulate apoptosis and tumor cell growth. Variants in VRK2 have been associated with schizophrenia. Alternative splicing results in multiple transcript variants that differ in their subcellular localization and biological activity.

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