AGTR1 Polyclonal Antibody, 100ul In vitro Assessment Mutations and deletions in NKX2-1

Mutations and deletions in NKX2-1 are associated with benign hereditary chorea

The protein is translocated from the Golgi apparatus to the nucleus in response to chemical anoxia and plays a role in regulation of cell death

The gene consists of 12 exons and the genomic structure is similar to that of neuregulin 1

additionally suggesting a metabolic function for the protein

it also regulates the splicing of fibronectin and CD45 genes

AGTR1 Polyclonal Antibody, 100ul In vitro Assessment Mutations and deletions in NKX2-1Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of