ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements A change in expression of

A change in expression of this protein has been noted in pancreatic cancer-derived cells

heart and brain

This enzyme is involved in creatine biosynthesis| whereby it catalyzes the transfer of a guanido group from L-arginine to glycine| resulting in guanidinoacetic acid| the immediate precursor of creatine

Defects in TRPS1 are a cause of tricho-rhino-phalangeal syndrome (TRPS) types I-III

CENPK is a subunit of a CENPH (MIM 605607)-CENPI (MIM 300065)-associated centromeric complex that targets CENPA (MIM 117139) to centromeres and is required for proper kinetochore function and mitotic progression (Okada et al

ZFY27 Rabbit Polyclonal Antibody, 50ul Supplements A change in expression ofThis gene encodes a protein with several transmembrane domains a Rab11 binding domain and a lipid binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia however the pathogenicity of the mutation which may simply represent a polymorphism is unclear.