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TPR Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection CREBBP is ubiquitously expressed and

SKU: 83820381403

4.8
SEK97.20 SEK117.20

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TPR Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection CREBBP is ubiquitously expressed andThis gene encodes a large coiled coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

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Description

CREBBP is ubiquitously expressed and is involved in the transcriptional coactivation of many different transcription factors

Homeodomain-interacting protein kinase 4 exhibits kinase activity and may phosphorylate the tumor suppressor protein p53

Transcripts from this gene contain a palindromic termination element

A similar protein in mice is required for proper neurulation

|PTM:The activation peptide is cleaved by factor IXa (in the intrinsic pathway)| or by factor VIIa (in the extrinsic pathway)

TPR Rabbit Polyclonal Antibody, 20ul Cell Separation and Collection CREBBP is ubiquitously expressed andThis gene encodes a large coiled coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

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