UBP14 Polyclonal Antibody, 100ul Buffer Solutions This gene encodes a member

This gene encodes a member of the transforming acidic colied-coil protein family

and are mitogens for several cell types

However| this gene product contains a KRAB domain (which is involved in protein-protein interactions) at the N-terminus| and a transposase domain at the C-terminus| suggesting that it may belong to the family of DNA-mediated transposons in human

This gene was identified upon genomic analysis of a gene-dense region at human chromosome 12p13

Cortactin is localized in the cytoplasm and in areas of the cell-substratum contacts

UBP14 Polyclonal Antibody, 100ul Buffer Solutions This gene encodes a memberThis gene encodes a member of the ubiquitin specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age