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EDAR Polyclonal Antibody, 100ul Plasma results in chronic myeloproliferative disorder

SKU: 83922106077

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EDAR Polyclonal Antibody, 100ul Plasma results in chronic myeloproliferative disorderThis gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor kappaB, JNK, and caspase independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

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Description

results in chronic myeloproliferative disorder with eosinophilia

maturation

Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM)

The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13

The encoded protein is primarily expressed in the epidermis| and plays a critical role in keratinocyte proliferation and differentiation

EDAR Polyclonal Antibody, 100ul Plasma results in chronic myeloproliferative disorderThis gene encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor kappaB, JNK, and caspase independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in this gene result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

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