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MLK3 Polyclonal Antibody, 100ul Metabolic enzymes May be involved in modulation

SKU: 84071938088

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PLN141.00 PLN179.00

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MLK3 Polyclonal Antibody, 100ul Metabolic enzymes May be involved in modulationThe protein encoded by MAP3K11 is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF kappaB mediated by Rho family GTPases

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Description

May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles

The functional enzyme is thought to be a homodimer which uses FAD as a cofactor

These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport

Among its related pathways are SMAD Signaling Network and Ubiquitin-Proteasome Dependent Proteolysis

Variation in ferritin subunit composition may affect the rates of iron uptake and release in different tissues

MLK3 Polyclonal Antibody, 100ul Metabolic enzymes May be involved in modulationThe protein encoded by MAP3K11 is a member of the serine threonine kinase family. This kinase contains a SH3 domain and a leucine zipper basic motif. This kinase preferentially activates MAPK8 JNK kinase, and functions as a positive regulator of JNK signaling pathway. This kinase can directly phosphorylate, and activates IkappaB kinase alpha and beta, and is found to be involved in the transcription activity of NF kappaB mediated by Rho family GTPases

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