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Hox-A1/B1/D1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in ITCH are a

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Hox-A1/B1/D1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in ITCH are aHOXB1 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.

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Description

Mutations in ITCH are a cause of syndromic multisystem autoimmune disease

Polymorphisms in this gene are associated with bipolar disorder and risk for schizophrenia

Multiple alternatively spliced transcript variants encoding different isoforms have been found for BARD1

GGH (gamma-glutamyl hydrolase)catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate

cell proliferation

Hox-A1/B1/D1 Polyclonal Antibody, 20ul Molecular Sciences Mutations in ITCH are aHOXB1 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.

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