LRRK1 Polyclonal Antibody, 50ul Buffer Solutions The encoded protein undergoes an

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to the cis/medial-Golgi where a second autocatalytic event takes place and the catalytic activity is acquired

mass spectrometry: PubMed:10614823

Dimerization with other BHLH proteins is required for efficient DNA binding

The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division

via the formation of a high-energy thioester bond

LRRK1 Polyclonal Antibody, 50ul Buffer Solutions The encoded protein undergoes anThe phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions in eukaryotes, including cell division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the serine threonine (Ser Thr) protein kinases. LRRK1 (leucine rich repeat serine threonine protein kinase 1), also known as RIPK6, Roco1 or KIAA1790, is a 2038