PAK Alpha Polyclonal Antibody, 50ul[BT-AP06895] Drug Development and Evaluation |PTM:Phosphorylated when associated with the

|PTM:Phosphorylated when associated with the catalytic subunit

microtubule dynamics

Multiple alternatively spliced transcript variants which encode different protein isoforms have been found for this gene

It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator

converting specific trimethylated histone residues to the dimethylated form

PAK Alpha Polyclonal Antibody, 50ul[BT-AP06895] Drug Development and Evaluation |PTM:Phosphorylated when associated with thePAK1 encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.